Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 14/20 | 0.40 |
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2003078 | 0.92 | CPT1A (0.42) | CPT1ACNR2CNR1RPS6KA2CYP2C8 | |
| SCHEMBL2002514 | 0.83 | CPT1A (0.45) | CPT1ALMNATSHRNPC1ALDH1A1 | |
| SCHEMBL2003147 | 0.80 | CPT1A (0.43) | CPT1ACNR2CNR1LMNATSHR | |
| SCHEMBL1997441 | 0.79 | CPT1A (0.43) | CPT1ALMNATSHRNPC1ALDH1A1 | |
| SCHEMBL2000336 | 0.78 | SMN1; SMN2 (0.44) | CPT1ACNR2CNR1LMNAALDH1A1 | |
| SCHEMBL1998105 | 0.76 | CPT1A (0.45) | CPT1ACNR2NPC1ALDH1A1 | |
| SCHEMBL2001296 | 0.76 | CPT1A (0.47) | CPT1ANPC1 | |
| SCHEMBL2001736 | 0.76 | CPT1A (0.47) | CPT1ACNR2CNR1RPS6KA2LMNA | |
| SCHEMBL2001377 | 0.75 | CPT1A (0.44) | CPT1ACNR2 | |
| SCHEMBL2003304 | 0.74 | CPT1A (0.47) | CPT1ACNR1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120660-A2 | SUBSTITUTED PYRIDOXAZINES | CARA THERAPEUTICS, INC. (US) | 2009-10-01 | — | — | WO | disclosed |