Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822949 | 0.92 | HTT (0.63) | HTTSMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL16352320 | 0.90 | SMN1; SMN2 (0.44) | HTTSMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13557150 | 0.90 | HTT (0.56) | HTTSMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9914257 | 0.87 | HTT (0.57) | HTTSMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13321958 | 0.87 | HTT (0.57) | HTTSMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL12341727 | 0.87 | HTT (0.57) | HTTSMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13670323 | 0.84 | MAPK14 (0.44) | HTTSMN1; SMN2ALDH1A1MAPTACHE | |
| SCHEMBL17808969 | 0.84 | HTT (0.53) | HTTSMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL17207929 | 0.83 | SMN1; SMN2 (0.51) | HTTSMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13266250 | 0.83 | HTT (0.47) | HTTSMN1; SMN2TDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090269645-A1 | POLYMER, POLYMER ELECTROLYTE AND FUEL CELL USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-10-29 | — | — | US | disclosed |