Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 2/20 | 0.52 |
| ▸ | RORC | P51449 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004021 | 0.89 | CPT1A (0.53) | CPT1ARORCNPC1CYP2C9LMNA | |
| SCHEMBL2005380 | 0.88 | CPT1A (0.49) | CPT1ARORCNPC1CYP2C9LMNA | |
| SCHEMBL2001117 | 0.80 | CPT1A (0.56) | CPT1ARORCNPC1CYP2C9KMT2A | |
| SCHEMBL2001102 | 0.79 | CPT1A (0.56) | CPT1ARORCNPC1CYP2C9HTR6 | |
| SCHEMBL12569922 | 0.79 | CPT1A (0.54) | CPT1ARORCNPC1CYP2C9LMNA | |
| SCHEMBL2005194 | 0.79 | CPT1A (0.53) | CPT1ARORCCYP2C9CNR1CNR2 | |
| SCHEMBL2005198 | 0.79 | CPT1A (0.53) | CPT1ARORCCYP2C9CNR1CNR2 | |
| SCHEMBL2007284 | 0.78 | CPT1A (0.52) | CPT1ARORCCYP2C9KMT2AMCL1 | |
| SCHEMBL2000704 | 0.77 | CPT1A (0.48) | CPT1ARORCNPC1CYP2C9HPGDS | |
| SCHEMBL2003367 | 0.77 | CPT1A (0.52) | CPT1ARORCNPC1CYP2C9HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120660-A2 | SUBSTITUTED PYRIDOXAZINES | CARA THERAPEUTICS, INC. (US) | 2009-10-01 | — | — | WO | disclosed |