Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.54 |
| ▸ | PRKCB | P05771 | 13/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.51 |
| ▸ | CDK2 | P24941 | 4/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.51 |
| ▸ | CDK1 | P06493 | 3/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.51 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | PRKCG | P05129 | 6/20 | 0.51 |
| ▸ | PRKCA | P17252 | 5/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127715 | 0.90 | GSK3B (0.55) | GSK3BPRKCBCCNA2CDK2CCNB2 | |
| SCHEMBL4341571 | 0.79 | GSK3B (0.70) | GSK3BPRKCBCCNA2CDK2CCNB2 | |
| SCHEMBL13221735 | 0.78 | GSK3B (0.60) | GSK3BPRKCBCCNA2CDK2CCNB2 | |
| SCHEMBL13221732 | 0.78 | GSK3B (0.60) | GSK3BPRKCBCCNA2CDK2CCNB2 | |
| SCHEMBL1127779 | 0.77 | GSK3B (0.59) | GSK3BPRKCBCCNA2CDK2CCNB2 | |
| SCHEMBL2979250 | 0.77 | GSK3B (0.78) | GSK3BPRKCBCCNA2CDK2CCNB2 | |
| SCHEMBL2982826 | 0.77 | GSK3B (0.59) | GSK3BPRKCBCCNA2CDK2CCNB2 | |
| SCHEMBL13204261 | 0.77 | GSK3B (0.55) | GSK3BPRKCBCCNA2CDK2CCNB2 | |
| SCHEMBL2974640 | 0.77 | GSK3B (0.57) | GSK3BPRKCBCCNA2CDK2CCNB2 | |
| SCHEMBL2974611 | 0.77 | GSK3B (0.63) | GSK3BPRKCBCCNA2CDK2CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132068-A2 | TREATMENT OF PLURIPOTENT CELLS | CENTOCOR ORTHO BIOTECH INC. (US) | 2009-10-29 | — | — | WO | disclosed |