SCHEMBL13670758

SCHEMBL13670758

Ic1ccc2cc(-c3cccc4ccccc34)ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.46
ACMSD Q8TDX5 1/20 0.46
GSTP1 P09211 1/20 0.44
PIM1 P11309 2/20 0.43
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
HDAC8 Q9BY41 2/20 0.41
HDAC6 Q9UBN7 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALPL P05186 1/20 0.41
GAA P10253 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31742566 0.89 MCL1 (0.54) MCL1ACMSDGSTP1PIM1CA12
SCHEMBL26563963 0.88 CA12 (0.51) MCL1ACMSDPIM1CA12CA1
SCHEMBL598962 0.87 GSTP1 (0.57) MCL1ACMSDGSTP1PIM1CA12
SCHEMBL30274189 0.87 GSTP1 (0.57) MCL1ACMSDGSTP1PIM1CA12
SCHEMBL25177116 0.85 MCL1 (0.51) MCL1ACMSDGSTP1PIM1CA12
SCHEMBL29195637 0.85 MCL1 (0.51) MCL1ACMSDGSTP1PIM1CA12
SCHEMBL29986101 0.85 MCL1 (0.51) MCL1ACMSDGSTP1PIM1CA12
SCHEMBL1470544 0.85 MCL1 (0.51) MCL1ACMSDGSTP1PIM1CA12
SCHEMBL12952471 0.83 MCL1 (0.46) MCL1ACMSDCA12CA1CA2
SCHEMBL20623106 0.83 KDM4E (0.39) MCL1ACMSDPIM1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2110376-A1 Novel compounds for electronic material and organic electronic device using the same Gracel Display Inc. (KR) 2009-10-21 EP disclosed