SCHEMBL136719

SCHEMBL136719

N#Cc1ccccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30201156 1.00
Water SCHEMBL27994831 1.00 TSHR (0.50)
SCHEMBL2351623 0.97 TSHR (0.48)
SCHEMBL17818517 0.89 TSHR (0.50)
Nitrous Acid SCHEMBL28128691 0.87 TSHR (0.40)
SCHEMBL17712501 0.80 ESR2 (0.48)
SCHEMBL29543686 0.80 ESR2 (0.48)
SCHEMBL3386194 0.79 DYRK1A (0.47)
SCHEMBL31032883 0.79 DYRK1A (0.47)
Water SCHEMBL19410621 0.78 TSHR (0.63)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2558 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004697-A Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material 同济大学 2025-05-16 CN claimed
EP-3650120-B1 FLUIDIZED-BED CATALYST APPLICABLE TO HALOARYLNITRILE PRODUCTION, AND PREPARATION AND APPLICATION THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-09-18 EP claimed
EP-4255947-B1 METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-07-03 EP claimed
WO-2024109438-A1 PREPARATION PROCESS OF HIGH-PURITY LOW-IMPURITY 10-METHOXYIMINOSTILBENE 浙江华洋药业有限公司 2024-05-30 WO claimed
US-20240026065-A1 METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-01-25 US claimed
CN-117402116-A Process for the preparation of dibenzoazepine compounds and their use as interferon activator protein agonists 河北中科金辉药业有限公司 2024-01-16 CN claimed
CN-117105819-A Preparation method of intermediate of irbesartan isomer 浙江金立源药业有限公司 2023-11-24 CN claimed
EP-4255947-A1 METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE POLYMERS Covestro Deutschland AG (DE) 2023-10-11 EP claimed
CN-113582908-B Near-ultraviolet organic electroluminescent material based on phenylcyano, preparation method thereof and application thereof in OLED preparation 华南理工大学 2023-09-26 CN claimed
CN-116529281-A Process for producing thermoplastic polyoxazolidone polymers 科思创德国股份有限公司 2023-08-01 CN claimed
US-6392080-B1 FROM O-HALOBENZONITRILE WITH TOLYLMAGNESIUM HALIDE SANOFI-STNTH{DOT OVER (E)}LABO (FR) 2002-05-21 US claimed
EP-0931059-B1 METHOD FOR PREPARING A CYANOBIPHENYL SANOFI SYNTHELABO (FR) 2001-12-12 EP claimed
US-6121480-A LOW SPEED PALLADIUM-CATALYZED COUPLING OF ARYL GRIGNARD REAGENT WITH BROMOBENZONITRILE GREAT LAKES CHEMICAL KONSTANZ GMBH (DE) 2000-09-19 US claimed
EP-0931059-A1 METHOD FOR PREPARING A CYANOBIPHENYL SANOFI (FR) 1999-07-28 EP claimed
EP-0883603-A1 METHOD FOR PRODUCING UNSYMMETRICALLY SUBSTITUTED BIPHENYLS Great Lakes Chemical Konstanz GmbH (DE) 1998-12-16 EP claimed
WO-1998009941-A1 METHOD FOR PREPARING A CYANOBIPHENYL SANOFI (FR) 1998-03-12 WO claimed
WO-1997030970-A1 METHOD FOR PRODUCING UNSYMMETRICALLY SUBSTITUTED BIPHENYLS GREAT LAKES CHEMICAL KONSTANZ GMBH (DE) 1997-08-28 WO claimed
US-5159082-A Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound MITSUBISHI KASEI CORPORATION (JP) 1992-10-27 US claimed
EP-0405389-A1 Process for producing an aromatic compound Mitsubishi Chemical Corporation (JP) 1991-01-02 EP claimed
US-4201632-A Separation of phenol-, cyclohexanone-, and cyclohexylbenzene-containing mixtures employing a nitrile as extraction distillation solvent PHILLIPS PETROLEUM COMPANY (US) 1980-05-06 US claimed