Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520677 | 0.86 | MAPT (0.59) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL1520681 | 0.86 | MAPT (0.59) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| Water SCHEMBL6576232 | 0.85 | MAPT (0.58) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL31317782 | 0.80 | MAPT (0.73) | MAPTMAOBCTDSP1SMN1; SMN2HTT | |
| Acetic Acid SCHEMBL13673558 | 0.77 | MAPT (0.47) | MAPTMAOBCTDSP1SMN1; SMN2CYP3A4 | |
| Acetic Acid SCHEMBL13673562 | 0.77 | MAPT (0.47) | MAPTMAOBCTDSP1SMN1; SMN2CYP3A4 | |
| Acetic Acid SCHEMBL915670 | 0.76 | MAPT (0.46) | MAPTMAOBCTDSP1SMN1; SMN2CYP3A4 | |
| Acetic Acid SCHEMBL915671 | 0.76 | MAPT (0.46) | MAPTMAOBCTDSP1SMN1; SMN2CYP3A4 | |
| SCHEMBL13673547 | 0.76 | HTT (0.53) | MAPTMAOBHTTNPC1RAB9A | |
| SCHEMBL13673660 | 0.76 | HTT (0.74) | MAPTSMN1; SMN2HTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309609-B2 | Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands | ANAMAR AB (SE) | 2012-11-13 | — | — | US | disclosed |