Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.51 |
| ▸ | MTOR | P42345 | 11/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877565 | 0.90 | PIK3CA (0.60) | PIK3CAMTORHDAC1PIK3CGPIK3R1 | |
| Bicarbonate SCHEMBL13674694 | 0.86 | PIK3CA (0.47) | PIK3CAMTORHDAC1PIK3CGPIK3R1 | |
| SCHEMBL13674729 | 0.85 | PIK3CA (0.56) | PIK3CAMTORHDAC1PIK3CGPIK3R1 | |
| SCHEMBL2864746 | 0.84 | PIK3CA (0.57) | PIK3CAMTORHDAC1PIK3CGPIK3R1 | |
| SCHEMBL364150 | 0.81 | PIK3CA (0.43) | PIK3CAMTORHDAC1PIK3CGPIK3R1 | |
| SCHEMBL336204 | 0.81 | PIK3CA (0.67) | PIK3CAMTORHDAC1PIK3CGPIK3R1 | |
| SCHEMBL799244 | 0.81 | MTOR (0.47) | PIK3CAMTORHDAC1PIK3CGPIK3R1 | |
| Bicarbonate SCHEMBL366205 | 0.81 | PIK3CA (0.44) | PIK3CAMTORHDAC1PIK3CGPIK3R1 | |
| SCHEMBL27813714 | 0.79 | PIK3CA (0.57) | PIK3CAMTORHDAC1PIK3CGPIK3R1 | |
| SCHEMBL10263292 | 0.79 | PIK3CA (0.62) | PIK3CAMTORHDAC1PIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336132-B1 | MORPHOLINOPURINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2014-01-01 | — | — | EP | disclosed |
| US-8309546-B2 | Morpholinopurine derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-11-13 | — | — | US | disclosed |