Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13672294 | 0.87 | F10 (0.42) | F10F2ABCB11ST14CYP3A4 | |
| SCHEMBL4484924 | 0.87 | F10 (0.42) | F10F2ABCB11ST14CYP3A4 | |
| SCHEMBL4484919 | 0.87 | F10 (0.42) | F10F2ABCB11ST14CYP3A4 | |
| SCHEMBL4479109 | 0.75 | F10 (0.47) | F10F2ABCB11ST14CYP3A4 | |
| SCHEMBL13672264 | 0.74 | F10 (0.54) | F10F2ABCB11ST14 | |
| SCHEMBL4485110 | 0.74 | F10 (0.54) | F10F2ABCB11ST14 | |
| SCHEMBL4485107 | 0.74 | F10 (0.54) | F10F2ABCB11ST14 | |
| SCHEMBL14534487 | 0.72 | F10 (0.39) | F10F2ABCB11ST14CYP1A2 | |
| SCHEMBL4492159 | 0.71 | F10 (0.53) | F10 | |
| SCHEMBL4492161 | 0.71 | F10 (0.53) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601752-B2 | Pyrrolidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-10-13 | — | — | US | disclosed |