Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.62 |
| ▸ | AR | P10275 | 3/20 | 0.62 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13672886 | 0.81 | ESR1 (0.60) | ESR1ESR2ARVDR | |
| SCHEMBL3396335 | 0.78 | ESR1 (0.57) | ESR1ESR2ARVDR | |
| SCHEMBL30058620 | 0.78 | ESR1 (1.00) | ESR1ESR2ARVDR | |
| SCHEMBL837374 | 0.78 | ESR1 (1.00) | ESR1ESR2ARVDR | |
| SCHEMBL3390972 | 0.77 | ESR1 (0.78) | ESR1ESR2ARVDR | |
| SCHEMBL13675224 | 0.76 | ESR1 (0.54) | ESR1ESR2ARVDR | |
| SCHEMBL3393188 | 0.76 | ESR1 (0.54) | ESR1ESR2ARVDR | |
| SCHEMBL13203878 | 0.76 | ESR1 (0.79) | ESR1ESR2ARVDR | |
| SCHEMBL3393109 | 0.75 | ESR1 (0.53) | ESR1ESR2ARVDR | |
| SCHEMBL3388735 | 0.74 | ESR1 (0.78) | ESR1ESR2ARVDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601850-B2 | less hypercalcemic than 1a,25 dihydroxy vitamin D3; bone disorders, psoriasis | ELI LILLY AND COMPANY (US) | 2009-10-13 | — | — | US | disclosed |