Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 6/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1470668 | 0.84 | AR (0.40) | TNKSPARP1PARP15PARP14TNKS2 | |
| SCHEMBL1470665 | 0.84 | AR (0.40) | TNKSPARP1PARP15PARP14TNKS2 | |
| SCHEMBL28499130 | 0.78 | TNKS (0.43) | TNKSPARP1PARP15PARP14TNKS2 | |
| SCHEMBL23489757 | 0.75 | EIF2AK4 (0.42) | PARP1EIF2AK4HDAC1 | |
| SCHEMBL18826007 | 0.75 | EIF2AK4 (0.42) | PARP1EIF2AK4HDAC1 | |
| SCHEMBL29861831 | 0.75 | EIF2AK4 (0.42) | PARP1EIF2AK4HDAC1 | |
| SCHEMBL23489511 | 0.75 | EIF2AK4 (0.42) | PARP1EIF2AK4HDAC1 | |
| Hydrochloric Acid SCHEMBL23459166 | 0.74 | EIF2AK4 (0.41) | PARP1EIF2AK4HDAC1 | |
| Hydrochloric Acid SCHEMBL23459167 | 0.74 | EIF2AK4 (0.41) | PARP1EIF2AK4HDAC1 | |
| SCHEMBL1471343 | 0.74 | EIF2AK4 (0.52) | EIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264417-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR | KALYPSYS, INC. (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264417-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR | PPARG, PPARA, PPARD | TNKS 4084/4885PARP1 3689/4885PARP15 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.