⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101449 | 1.00 | — | — | |
| SCHEMBL13631556 | 1.00 | — | — | |
| SCHEMBL4478204 | 1.00 | — | — | |
| SCHEMBL13631670 | 1.00 | — | — | |
| SCHEMBL5509072 | 1.00 | — | — | |
| SCHEMBL13631555 | 1.00 | — | — | |
| SCHEMBL4477540 | 1.00 | — | — | |
| SCHEMBL12714294 | 0.90 | CA1 (0.34) | — | |
| SCHEMBL22078932 | 0.77 | CA1 (0.32) | — | |
| SCHEMBL22130744 | 0.77 | CA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163505-A1 | ARGINASE INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2021-06-03 | — | — | US | disclosed |
| US-20090258892-A1 | FUSED PYRAZOLE DERIVATIVES AND METHODS OF TREATMENT OF METABOLIC-RELATED DISORDERS THEREOF | ARENA PHARMACEUTICALS, INC. (US) | 2009-10-15 | — | — | US | disclosed |