SCHEMBL1367655

SCHEMBL1367655

O=C(O)CCC1(CCC(=O)O)CCCC(=O)C1(CCC(=O)O)CCC(=O)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
PTGER4 P35408 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8654035 0.89 NPC1 (0.32) NPC1
SCHEMBL12541025 0.70 MME (0.35) NPC1
SCHEMBL6752032 0.68 APEX1 (0.32) NPC1
SCHEMBL7495343 0.68 MME (0.39) NPC1
SCHEMBL7495347 0.68 MME (0.39) NPC1
SCHEMBL466683 0.67 SIRT2 (0.30)
SCHEMBL10729071 0.66 MME (0.37) NPC1
SCHEMBL11818292 0.66 TSHR (0.40)
SCHEMBL11818289 0.66 TSHR (0.40)
SCHEMBL10729067 0.66 MME (0.37) NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9096774-B2 Heat-curing powder-lacquer compositions yielding a matte surface after curing of the coating, as well as a simple method for production of same EVONIK DEGUSSA GMBH (DE) 2015-08-04 US disclosed
US-8524837-B2 Heat-curing powder-lacquer compositions yielding a matte surface after curing of the coating, as well as a simple method for production of same EVONIK DEGUSSA GMBH (DE) 2013-09-03 US disclosed
US-8476376-B2 Heat-curing powder-lacquer compositions yielding a matte surface after curing of the coating, as well as a simple method for production of same EVONIK DEGUSSA GMBH (DE) 2013-07-02 US disclosed
US-20130041103-A1 HEAT-CURABLE POWDER COATING COMPOSITIONS, WHICH AFTER THE COATING HAS CURED RESULT IN A MATT SURFACE AND SIMPLE METHOD FOR PRODUCING SAME EVONIK DEGUSSA GMBH (DE) 2013-02-14 US disclosed
US-20110288202-A1 HEAT-CURING POWDER-LACQUER COMPOSITIONS YIELDING A MATTE SURFACE AFTER CURING OF THE COATING, AS WELL AS A SIMPLE METHOD FOR PRODUCTION OF SAME EVONIK DEGUSSA GMBH (DE) 2011-11-24 US disclosed
US-20110224378-A1 Heat-curing powder-lacquer compositions yielding a matte surface after curing of the coating, as well as a simple method for production of same EVONIK DEGUSSA GMBH (DE) 2011-09-15 US disclosed
EP-1669385-B1 Continuous method for manufacturing an acid functional blocked solid isocyanate BAYER MATERIALSCIENCE LLC (US) 2011-05-04 EP disclosed
EP-1669385-A1 Continuous method for manufacturing an acid functional blocked solid isocyanate Bayer MaterialScience LLC (US) 2006-06-14 EP disclosed
US-20060122357-A1 Continuous method for manufacturing an acid functional blocked solid isocyanate BAYER MATERIALSCIENCE LLC 2006-06-08 US disclosed
EP-0698645-B1 Heat-curable coating compositions INVENTA AG (CH) 2001-02-28 EP disclosed
EP-0698629-B1 Epoxy-free heat-curable coating system INVENTA AG (CH) 2000-05-17 EP disclosed
US-5741602-A MIXTURE OF COATING POWDERS EACH COMPRISING BINDER RESIN COMPOSED OF CARBOXY-TERMINATED POLYESTER RESIN, COMPONENT HAVING AT LEAST TWO BETA-HYDROXYALKYLAMIDE GROUPS PER MOLECULE EMS-INVENTA AG (CH) 1998-04-21 US disclosed
US-5538759-A HYDROXY-TERMINATED POLYESTER, CARBOXY GROUP-CONTAINING BLOCKED POLYISOCYANATE, HYDROXYALKYLAMIDE EMS-INVENTA AG (CH) 1996-07-23 US disclosed
EP-0698645-A2 Heat-curable coating compositions EMS-INVENTA AG (CH) 1996-02-28 EP disclosed
EP-0698629-A2 Epoxy-free heat-curable coating system EMS-INVENTA AG (CH) 1996-02-28 EP disclosed
EP-0366608-B1 Powder coating useful as a mat coating CIBA GEIGY AG (CH) 1993-12-15 EP disclosed