Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.63 |
| ▸ | RARB | P10826 | 4/20 | 0.59 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28053122 | 1.00 | TP53 (0.65) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| Benzoic Acid SCHEMBL12981201 | 0.98 | TSHR (0.62) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| Benzoic Acid SCHEMBL12971418 | 0.93 | TP53 (0.57) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| Benzoic Acid SCHEMBL12981029 | 0.93 | TP53 (0.61) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| Benzoic Acid SCHEMBL19411715 | 0.93 | RARB (0.64) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| Triethylene Glycol SCHEMBL12971248 | 0.92 | MEN1 (0.61) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| Benzoic Acid SCHEMBL11325743 | 0.92 | TSHR (0.55) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| Triethylene Glycol SCHEMBL12971315 | 0.90 | MEN1 (0.58) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| Benzoic Acid SCHEMBL27497025 | 0.89 | TSHR (0.65) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| Undecane SCHEMBL15129102 | 0.89 | TSHR (0.64) | TP53TSHRPLA2G4BRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 565 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11648187-B2 | Topical skin formulation | MARY KAY INC. (US) | 2023-05-16 | — | — | US | claimed |
| EP-3195849-B1 | UV BLOCKING FUNCTIONAL COMPOSITE POWDER PREPARED BY DOUBLY COATING INORGANIC POWDER WITH INORGANIC UV BLOCKING AGENT AND ORGANIC UV ABSORBER, AND UV BLOCKING COSMETIC COMPOSITION USING SAME | CHEMLAND CO LTD (KR) | 2021-07-28 | — | — | EP | claimed |
| US-10682302-B2 | Cosmetic compositions | MARY KAY INC. (US) | 2020-06-16 | — | — | US | claimed |
| US-20200121568-A1 | TOPICAL SKIN FORMULATION | MARY KAY INC. | 2020-04-23 | — | — | US | claimed |
| US-10548821-B2 | Topical skin formulation | MARY KAY INC. (US) | 2020-02-04 | — | — | US | claimed |
| EP-2007363-B1 | ANTI-MICROBIAL HAND TOWEL WITH TIME-DELAY CHROMATIC TRANSFER INDICATOR AND ABSORBENCY RATE DELAY | GPCP IP HOLDINGS LLC (US) | 2018-07-18 | — | — | EP | claimed |
| US-20180161265-A1 | COSMETIC COMPOSITIONS | MARY KAY INC. | 2018-06-14 | — | — | US | claimed |
| EP-2897579-B1 | COMPOSITIONS AND ARTICLES HAVING A PARENT FRAGRANCE AND MICROCAPSULES ENCAPSULATING A NON-PARENT FRAGRANCE | PROCTER & GAMBLE (US) | 2018-02-21 | — | — | EP | claimed |
| EP-3195849-A1 | UV BLOCKING FUNCTIONAL COMPOSITE POWDER PREPARED BY DOUBLY COATING INORGANIC POWDER WITH INORGANIC UV BLOCKING AGENT AND ORGANIC UV ABSORBER, AND UV BLOCKING COSMETIC COMPOSITION USING SAME | Chemland. Co., Ltd. (KR) | 2017-07-26 | — | — | EP | claimed |
| US-9668952-B2 | Sunscreen formulations | MARY KAY INC. (US) | 2017-06-06 | — | — | US | claimed |
| US-20020064541-A1 | Composition exhibiting enhanced formulation stability and delivery of topical active ingredients | SOL-GEL TECHNOLOGIES LTD. (IL) | 2002-05-30 | — | — | US | claimed |
| US-6383505-B1 | Fast-acting antimicrobial lotion with enhanced efficacy | STERIS INC | 2002-05-07 | — | — | US | claimed |
| EP-1180011-A1 | NOVEL DELIVERY SYSTEM FOR INORGANIC SUNSCREENS | FINETEX, INC. (US) | 2002-02-20 | — | — | EP | claimed |
| WO-2001080823-A2 | COMPOSITION EXHIBITING ENHANCED FORMULATION STABILITY AND DELIVERY OF TROPICAL ACTIVE INGREDIENTS | SOL-GEL TECHNOLOGIES LTD. (IL) | 2001-11-01 | — | — | WO | claimed |
| WO-2001072276-A1 | NOVEL DELIVERY SYSTEM FOR INORGANIC SUNSCREENS | FINETEX, INC. (US) | 2001-10-04 | — | — | WO | claimed |
| US-6261713-B1 | Delivery system for inorganic sunscreens | FINETEX, INC. | 2001-07-17 | — | — | US | claimed |
| US-5871763-A | EMOLLIENTS FOR SKINS | FORT JAMES CORPORATION (US) | 1999-02-16 | — | — | US | claimed |
| EP-0875233-A1 | Substrate treated with lotion | Fort James Corporation (US) | 1998-11-04 | — | — | EP | claimed |
| EP-0511652-B1 | Hair shampoo composition to impart improved hair conditioning properties | CURTIS HELENE IND INC (US) | 1995-11-29 | — | — | EP | claimed |
| EP-0511652-A1 | Hair shampoo composition to impart improved hair conditioning properties | HELENE CURTIS, INC. (US) | 1992-11-04 | — | — | EP | claimed |