Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.78 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13677849 | 0.87 | F10 (0.81) | F10PTGS2 | |
| SCHEMBL13677853 | 0.87 | F10 (0.77) | F10PTGS2 | |
| SCHEMBL1405952 | 0.87 | F10 (0.77) | F10PTGS2 | |
| SCHEMBL8268508 | 0.86 | F10 (0.82) | F10PTGS2 | |
| SCHEMBL13677854 | 0.86 | F10 (0.82) | F10PTGS2 | |
| SCHEMBL1406068 | 0.85 | F10 (0.81) | F10PTGS2 | |
| SCHEMBL13890614 | 0.84 | F10 (0.79) | F10PTGS2 | |
| SCHEMBL1405858 | 0.84 | F10 (0.85) | F10 | |
| SCHEMBL1405810 | 0.84 | F10 (0.85) | F10 | |
| SCHEMBL13677855 | 0.84 | F10 (0.72) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598241-B2 | 2-[3-(4-chlorophenyl)ureido] N-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-4-methanesulfonylbutyramide; prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors | MERCK PATENT GMBH (DE) | 2009-10-06 | — | — | US | disclosed |