Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 16/20 | 0.49 |
| ▸ | CA1 | P00915 | 15/20 | 0.49 |
| ▸ | CA2 | P00918 | 15/20 | 0.49 |
| ▸ | CA12 | O43570 | 7/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14526777 | 0.87 | CA9 (0.56) | CA9CA1CA2CA12CA14 | |
| SCHEMBL15372440 | 0.84 | CA9 (0.59) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14401673 | 0.83 | CA9 (0.61) | CA9CA1CA2CA12CA14 | |
| SCHEMBL1688096 | 0.81 | CA9 (0.52) | CA9CA1CA2CA12CA14 | |
| SCHEMBL15432797 | 0.81 | CA9 (0.52) | CA9CA1CA2CA12CA14 | |
| SCHEMBL29837449 | 0.81 | CA9 (0.52) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14620245 | 0.81 | FOLH1 (0.53) | CA9CA1CA2CA12USP2 | |
| SCHEMBL15150500 | 0.81 | CA9 (0.59) | CA9CA1CA2CA12CA14 | |
| SCHEMBL13678633 | 0.81 | FOLH1 (0.50) | CA9CA1CA2CA12USP2 | |
| SCHEMBL14527509 | 0.80 | CA9 (0.66) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1540347-B1 | DETECTING RECEPTOR OLIGOMERIZATION | ACLARA BIOSCIENCES INC (US) | 2009-09-09 | — | — | EP | disclosed |
| US-20090011432-A1 | Detecting and Profiling Molecular Complexes | MONOGRAM BIOSCIENCES, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| US-7402397-B2 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. (US) | 2008-07-22 | — | — | US | disclosed |