SCHEMBL13679031

SCHEMBL13679031

C=NN(C)/N=C(\N)N1CCCC(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(C)=O)c2ccc(Cl)cc21

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CETP P11597 10/20 0.40
TACR1 P25103 5/20 0.37
CCR1 P32246 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3528213 0.89 CETP (0.44) CETPTACR1CCR1
SCHEMBL3533427 0.87 CETP (0.45) CETPTACR1CCR1
SCHEMBL3533722 0.86 CETP (0.46) CETPTACR1CCR1
SCHEMBL3531845 0.85 CETP (0.42) CETPTACR1CCR1
SCHEMBL3531692 0.84 CETP (0.42) CETPTACR1CCR1
SCHEMBL3536714 0.82 CETP (0.45) CETPTACR1CCR1
SCHEMBL3538476 0.82 CETP (0.43) CETPTACR1CCR1
SCHEMBL1385788 0.82 CETP (0.54) CETP
SCHEMBL3530071 0.82 CETP (0.54) CETP
SCHEMBL3538809 0.82 CETP (0.54) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2098512-A1 Compounds and methods for treating dyslipidemia Eli Lilly & Company (US) 2009-09-09 EP disclosed