Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.52 |
| ▸ | HTR2A | P28223 | 19/20 | 0.52 |
| ▸ | HTR2B | P41595 | 18/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13679034 | 0.86 | HTR2C (0.53) | HTR2CHTR2AHTR2B | |
| SCHEMBL1096662 | 0.85 | HTR2A (0.66) | HTR2CHTR2AHTR2B | |
| SCHEMBL1095337 | 0.85 | HTR2C (0.73) | HTR2CHTR2AHTR2B | |
| SCHEMBL1095023 | 0.85 | HTR2A (0.66) | HTR2CHTR2AHTR2B | |
| SCHEMBL1095335 | 0.85 | HTR2C (0.73) | HTR2CHTR2AHTR2B | |
| SCHEMBL1096664 | 0.85 | HTR2A (0.66) | HTR2CHTR2AHTR2B | |
| SCHEMBL1095360 | 0.85 | HTR2C (0.66) | HTR2CHTR2AHTR2B | |
| SCHEMBL1095158 | 0.85 | HTR2C (0.66) | HTR2CHTR2AHTR2B | |
| SCHEMBL1095359 | 0.85 | HTR2C (0.66) | HTR2CHTR2AHTR2B | |
| SCHEMBL1096554 | 0.85 | HTR2C (0.73) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833473-B1 | 5HT2C RECEPTOR MODULATOR COMPOSITIONS AND METHODS OF USE | ARENA PHARM INC (US) | 2009-09-09 | — | — | EP | disclosed |