Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13456845 | 0.84 | — | — | |
| SCHEMBL20220546 | 0.84 | TSHR (0.50) | TSHRALDH1A1PLA2G2C | |
| SCHEMBL1455036 | 0.82 | TSHR (0.31) | TSHR | |
| SCHEMBL14137876 | 0.80 | TSHR (0.40) | TSHRALDH1A1PLA2G2C | |
| SCHEMBL4486364 | 0.80 | — | — | |
| SCHEMBL4349371 | 0.79 | — | — | |
| SCHEMBL1454157 | 0.79 | — | — | |
| SCHEMBL386978 | 0.77 | — | — | |
| SCHEMBL2110564 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL18533162 | 0.74 | TSHR (0.42) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2103619-A1 | IMIDAZOTHIAZOLE DERIVATIVES | Daiichi Sankyo Company, Limited (JP) | 2009-09-23 | — | — | EP | disclosed |