Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.73 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13679656 | 0.88 | ABCB1 (0.70) | ABCB1NOX1PTPN1MAPTMAPK13 | |
| SCHEMBL3826448 | 0.84 | ABCB1 (1.00) | ABCB1NOX1PTPN1MAPTMAPK13 | |
| SCHEMBL719050 | 0.84 | ABCB1 (1.00) | ABCB1NOX1PTPN1MAPTMAPK13 | |
| SCHEMBL6625154 | 0.83 | ABCB1 (0.69) | ABCB1NOX1PTPN1MAPTMAPK13 | |
| SCHEMBL3829640 | 0.82 | ABCB1 (0.91) | ABCB1NOX1PTPN1MAPTMAPK13 | |
| SCHEMBL13679717 | 0.82 | ABCB1 (0.91) | ABCB1NOX1PTPN1MAPTMAPK13 | |
| SCHEMBL719051 | 0.82 | ABCB1 (0.74) | ABCB1NOX1PTPN1MAPTMAPK13 | |
| SCHEMBL4442601 | 0.82 | ABCB1 (0.68) | ABCB1NOX1PTPN1MAPTMAPK13 | |
| SCHEMBL3830858 | 0.81 | ABCB1 (0.92) | ABCB1NOX1PTPN1MAPTMAPK13 | |
| SCHEMBL13679699 | 0.81 | ABCB1 (0.92) | ABCB1NOX1PTPN1MAPTMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999835-B1 | IMIDAZOLE DERIVATIVES AS MDR MODULATORS | TAIJI BIOMEDICAL INC (US) | 2009-09-09 | — | — | EP | disclosed |
| EP-2082740-A2 | Use of imidazole derivatives as MDR modulators | Taiji Biomedical, Inc. (US) | 2009-07-29 | — | — | EP | disclosed |