Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16692933 | 0.92 | BRAF (0.82) | BRAFRAF1 | |
| SCHEMBL1013114 | 0.90 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL13680207 | 0.89 | BRAF (0.82) | BRAFRAF1 | |
| SCHEMBL18676545 | 0.89 | BRAF (0.77) | BRAFRAF1 | |
| SCHEMBL13680230 | 0.86 | BRAF (0.83) | BRAFRAF1 | |
| SCHEMBL1013249 | 0.86 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL1011886 | 0.86 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL1081741 | 0.84 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL1014971 | 0.84 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL1013064 | 0.84 | BRAF (0.88) | BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117080-A1 | QUINAZOLINE DERIVATIVES AS RAF KINASE MODULATORS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATON (US) | 2009-09-24 | — | — | WO | disclosed |