Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012968 | 0.90 | BRAF (1.00) | BRAFRAF1 | |
| Hydrochloric Acid SCHEMBL1013667 | 0.89 | BRAF (0.98) | BRAFRAF1 | |
| SCHEMBL18676482 | 0.87 | BRAF (0.64) | BRAFRAF1 | |
| SCHEMBL1012269 | 0.87 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL1014780 | 0.87 | BRAF (1.00) | BRAFRAF1 | |
| SCHEMBL18676593 | 0.87 | BRAF (0.65) | BRAFRAF1 | |
| Hydrochloric Acid SCHEMBL1012255 | 0.86 | BRAF (0.98) | BRAFRAF1 | |
| SCHEMBL16692935 | 0.85 | BRAF (0.67) | BRAFRAF1 | |
| SCHEMBL16692933 | 0.83 | BRAF (0.82) | BRAFRAF1 | |
| SCHEMBL18676405 | 0.82 | BRAF (0.59) | BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117080-A1 | QUINAZOLINE DERIVATIVES AS RAF KINASE MODULATORS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATON (US) | 2009-09-24 | — | — | WO | disclosed |