Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12190763 | 1.00 | TTR (0.46) | TTRDPP4P2RY12CA12CA1 | |
| SCHEMBL12190633 | 0.92 | TTR (0.46) | TTRDPP4P2RY12CA12CA1 | |
| SCHEMBL12190734 | 0.90 | APP (0.49) | P2RY12ACHEBCHEALOX5HDAC1 | |
| SCHEMBL973374 | 0.89 | AKT1 (0.47) | TTRP2RY12CA12CA1CA2 | |
| SCHEMBL973372 | 0.89 | AKT1 (0.47) | TTRP2RY12CA12CA1CA2 | |
| SCHEMBL6368019 | 0.85 | HDAC1 (0.41) | FDPSHDAC1AKT1 | |
| SCHEMBL12869649 | 0.83 | TTR (0.47) | TTRDPP4P2RY12CA12CA1 | |
| SCHEMBL15109310 | 0.82 | TTR (0.46) | TTRDPP4P2RY12CA12CA1 | |
| SCHEMBL974029 | 0.80 | HDAC1 (0.47) | TTRCA12CA1CA2CA7 | |
| SCHEMBL974028 | 0.80 | HDAC1 (0.47) | TTRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582770-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-01 | — | — | US | disclosed |