Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.57 |
| ▸ | CCR8 | P51685 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1456176 | 0.84 | CCR1 (0.80) | CCR1CCR8NPC1RAB9ATP53 | |
| SCHEMBL1456112 | 0.84 | CCR1 (0.80) | CCR1CCR8NPC1RAB9ATP53 | |
| SCHEMBL1456390 | 0.84 | CCR1 (0.80) | CCR1CCR8NPC1RAB9ATP53 | |
| SCHEMBL4169259 | 0.82 | CCR1 (0.76) | CCR1CCR8NPC1RAB9ATP53 | |
| SCHEMBL16715989 | 0.82 | CCR1 (0.76) | CCR1CCR8NPC1RAB9ATP53 | |
| SCHEMBL4174080 | 0.82 | CCR1 (0.76) | CCR1CCR8NPC1RAB9ATP53 | |
| SCHEMBL3753156 | 0.82 | CCR1 (0.76) | CCR1CCR8NPC1RAB9ATP53 | |
| SCHEMBL4176950 | 0.82 | CCR1 (0.76) | CCR1CCR8NPC1RAB9ATP53 | |
| Hydrochloric Acid SCHEMBL4171256 | 0.81 | CCR1 (0.73) | CCR1CCR8NPC1RAB9ATP53 | |
| SCHEMBL4184174 | 0.79 | CCR1 (0.70) | CCR1CCR8NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |