Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 11/20 | 0.36 |
| ▸ | CNR1 | P21554 | 7/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59244 | 1.00 | TUBB1 (0.57) | TUBB1CNR2CNR1ELANEOPRK1 | |
| SCHEMBL13682114 | 0.99 | TUBB1 (0.56) | TUBB1CNR2CNR1ELANE | |
| SCHEMBL58612 | 0.99 | TUBB1 (0.58) | TUBB1CNR2CNR1ELANE | |
| SCHEMBL13682200 | 0.99 | TUBB1 (0.58) | TUBB1CNR2CNR1ELANE | |
| SCHEMBL58400 | 0.99 | TUBB1 (0.56) | TUBB1CNR2CNR1ELANE | |
| SCHEMBL13682115 | 0.98 | TUBB1 (0.57) | TUBB1CNR2CNR1ELANEOPRK1 | |
| SCHEMBL59464 | 0.98 | TUBB1 (0.57) | TUBB1CNR2CNR1ELANEOPRK1 | |
| SCHEMBL12201775 | 0.92 | TUBB1 (0.48) | TUBB1CNR2CNR1 | |
| SCHEMBL18421085 | 0.88 | TUBB1 (0.59) | TUBB1ELANE | |
| SCHEMBL14592398 | 0.88 | TUBB1 (0.59) | TUBB1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585976-B2 | Hemiasterlin derivatives and uses thereof | EISAI CO., LTD. (JP) | 2009-09-08 | — | — | US | disclosed |
| US-7192972-B2 | Hemiasterlin derivatives and uses thereof | EISAI CO., LTD. (JP) | 2007-03-20 | — | — | US | disclosed |