Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 14/20 | 0.35 |
| ▸ | MMP3 | P08254 | 8/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57708 | 0.91 | TUBB1 (0.51) | TUBB1MMP2MMP3MMP1ADAM17 | |
| SCHEMBL13848005 | 0.91 | TUBB1 (0.51) | TUBB1MMP2MMP3MMP1ADAM17 | |
| SCHEMBL13847979 | 0.90 | TUBB1 (0.55) | TUBB1MMP2MMP3MMP1ADAM17 | |
| SCHEMBL58456 | 0.90 | TUBB1 (0.55) | TUBB1MMP2MMP3MMP1ADAM17 | |
| SCHEMBL58061 | 0.89 | TUBB1 (0.53) | TUBB1MMP2MMP3MMP1ADAM17 | |
| SCHEMBL13848002 | 0.89 | TUBB1 (0.53) | TUBB1MMP2MMP3MMP1ADAM17 | |
| SCHEMBL13848945 | 0.89 | TUBB1 (0.49) | TUBB1MMP2MMP3MMP1ADAM17 | |
| SCHEMBL58406 | 0.89 | TUBB1 (0.49) | TUBB1MMP2MMP3MMP1ADAM17 | |
| SCHEMBL58365 | 0.85 | TUBB1 (0.55) | TUBB1MMP2MMP3MMP1ADAM17 | |
| SCHEMBL14186790 | 0.84 | TUBB1 (0.51) | TUBB1MMP2MMP3MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585976-B2 | Hemiasterlin derivatives and uses thereof | EISAI CO., LTD. (JP) | 2009-09-08 | — | — | US | disclosed |