Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13184190 | 0.74 | HCAR2 (0.44) | HCAR2DYRK1A | |
| SCHEMBL9126671 | 0.71 | — | — | |
| SCHEMBL13683068 | 0.62 | — | — | |
| SCHEMBL12354209 | 0.62 | DYRK1A (0.48) | DYRK1A | |
| Hydrogen Sulfide SCHEMBL28167473 | 0.61 | GAA (0.31) | — | |
| Isopropyl Alcohol SCHEMBL7702781 | 0.61 | DYRK1A (0.41) | DYRK1ALMNAL3MBTL1 | |
| SCHEMBL14044080 | 0.61 | HCAR2 (0.70) | HCAR2 | |
| SCHEMBL19499607 | 0.61 | DYRK1A (0.35) | DYRK1A | |
| Isopropyl Alcohol SCHEMBL8848150 | 0.60 | DYRK1A (0.39) | DYRK1ALMNAL3MBTL1 | |
| SCHEMBL3464222 | 0.59 | HCAR2 (0.42) | HCAR2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589199-B2 | Substituted piperazines | CHEMOCENTRYX, INC. (US) | 2009-09-15 | — | — | US | disclosed |