SCHEMBL13684277

SCHEMBL13684277

CC(=O)C/C(C)=N/NC(=O)COCC(=O)NCCOCCOCCn1cc(CNC(=O)C2CCC(CN3C(=O)CC(C)C3=O)CC2)nn1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 1/20 0.42
▸ IL2 P60568 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16062727 0.95 TTR (0.43) TTRIL2
SCHEMBL12342488 0.92 TTR (0.46) TTRIL2
SCHEMBL13684272 0.92 TTR (0.46) TTRIL2
SCHEMBL25559708 0.91 TTR (0.45) TTRIL2
SCHEMBL14129407 0.89 TTR (0.45) TTRIL2
SCHEMBL13402834 0.87 TTR (0.46) TTRIL2
SCHEMBL13540856 0.87 TTR (0.45) TTRIL2
SCHEMBL12020709 0.85 TTR (0.43) TTRIL2
SCHEMBL12020802 0.84 TTR (0.42) TTRIL2
SCHEMBL12377441 0.84 TTR (0.46) TTRIL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7591994-B2 Improved targetting IMMUNOMEDICS, INC. (US) 2009-09-22 — — US disclosed
US-20080166363-A1 Improved targetting IMMUNOMEDICS, INC. 2008-07-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080166363-A1 Improved targetting CD47, CYTH3, FCGR2A TTR 4273/4885IL2 893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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