SCHEMBL13685685

SCHEMBL13685685

Cc1cc(C(C)NC(=O)C2CC2(C)c2ccc(C(C)(C)C)nc2)ccc1NS(C)(=O)=O

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 8/20 0.36
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1473768 1.00 TRPV1 (0.36) TRPV1HPGD
Hydrochloric Acid SCHEMBL1474669 0.99 TRPV1 (0.36) TRPV1HPGD
SCHEMBL1474076 0.92 TRPV1 (0.42) TRPV1
SCHEMBL5823096 0.92 TRPV1 (0.42) TRPV1
SCHEMBL12827553 0.92 TRPV1 (0.42) TRPV1
SCHEMBL1473659 0.84 TRPV1 (0.39) TRPV1HPGD
SCHEMBL13685622 0.84 TRPV1 (0.39) TRPV1HPGD
SCHEMBL1474455 0.84 TRPV1 (0.39) TRPV1HPGD
SCHEMBL5326494 0.84 TRPV1 (0.37) TRPV1
SCHEMBL13838849 0.83 HPGD (0.38) TRPV1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1861359-B1 N-(N-SULFONYLAMINOMETHYL)CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN PFIZER (US) 2012-11-14 EP disclosed