Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1474524 | 1.00 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL13622433 | 0.93 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL1475987 | 0.90 | TRPV1 (0.37) | TRPV1 | |
| SCHEMBL12747840 | 0.84 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL12827241 | 0.84 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL1474350 | 0.84 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL12747893 | 0.84 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL1473960 | 0.84 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL1473906 | 0.84 | TRPV1 (0.33) | TRPV1 | |
| SCHEMBL13685634 | 0.84 | TRPV1 (0.33) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861359-B1 | N-(N-SULFONYLAMINOMETHYL)CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | PFIZER (US) | 2012-11-14 | — | — | EP | disclosed |