Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 13/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | SOD1 | P00441 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11932375 | 0.87 | CSNK2A1 (0.50) | CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL10134928 | 0.85 | CSNK2A1 (0.45) | CSNK2A1CSNK2A2CSNK2BSOD1ALDH1A1 | |
| SCHEMBL13688041 | 0.80 | CSNK2A1 (0.46) | CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL13688067 | 0.80 | CSNK2A1 (0.71) | CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL10169235 | 0.79 | CSNK2A1 (0.69) | CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL13688053 | 0.78 | CSNK2A1 (0.56) | CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL13688009 | 0.77 | CSNK2A1 (0.72) | CSNK2A1CSNK2A2CSNK2BALDH1A1SMN1; SMN2 | |
| SCHEMBL12255832 | 0.76 | CSNK2A1 (0.69) | CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL11932690 | 0.76 | CSNK2A1 (0.50) | CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL13688045 | 0.76 | CSNK2A1 (0.50) | CSNK2A1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108912-A1 | PROTEIN KINASE MODULATORS | CYLENE PHARMACEUTICALS, INC. (US) | 2009-09-03 | — | — | WO | disclosed |