Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13688063 | 0.92 | CSNK2A1 (0.42) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10134875 | 0.86 | SLC6A4 (0.40) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL13688079 | 0.84 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10134879 | 0.82 | KDM4E (0.38) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10134962 | 0.79 | CSNK2A1 (0.41) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10132574 | 0.78 | CSNK2A1 (0.61) | CSNK2A1 | |
| SCHEMBL10132329 | 0.75 | CSNK2A1 (0.42) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10132276 | 0.75 | CSNK2A1 (0.42) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10132325 | 0.75 | CSNK2A1 (0.42) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10134878 | 0.72 | SLC6A4 (0.41) | LMNAIRAK4PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108912-A1 | PROTEIN KINASE MODULATORS | CYLENE PHARMACEUTICALS, INC. (US) | 2009-09-03 | — | — | WO | disclosed |