Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.54 |
| ▸ | CNR2 | P34972 | 4/20 | 0.54 |
| ▸ | HTR3A | P46098 | 7/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060702 | 0.92 | CNR1 (0.52) | CNR1CNR2HTR3AF10ALDH1A1 | |
| SCHEMBL13691003 | 0.86 | CNR1 (0.64) | CNR1CNR2HTR3AF10ALDH1A1 | |
| SCHEMBL13690611 | 0.85 | CNR1 (0.63) | CNR1CNR2HTR3AF10ALDH1A1 | |
| SCHEMBL13691103 | 0.84 | CNR1 (0.61) | CNR1CNR2HTR3AHDAC1HDAC6 | |
| SCHEMBL13690658 | 0.84 | CNR1 (0.58) | CNR1CNR2HTR3AALDH1A1CYP3A4 | |
| SCHEMBL4051967 | 0.84 | CNR1 (0.51) | CNR1CNR2HTR3AF10ALDH1A1 | |
| SCHEMBL13690582 | 0.84 | CNR1 (0.51) | CNR1CNR2HTR3AF10ALDH1A1 | |
| SCHEMBL4056304 | 0.83 | CNR1 (0.58) | CNR1CNR2HTR3AHDAC1HDAC6 | |
| SCHEMBL13690945 | 0.83 | CNR1 (0.52) | CNR1CNR2HTR3AF10ALDH1A1 | |
| SCHEMBL12885498 | 0.82 | CNR1 (0.49) | CNR1CNR2HTR3AF10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |