SCHEMBL13691985

SCHEMBL13691985

COC(C)c1nc2c(c(-c3ccc(F)cc3)c1C(O)c1ccc(C(F)(F)F)cc1)[C@@H](O)CC(C)(C)C2

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL971353 0.87 CETP (0.48) CETP
SCHEMBL13691982 0.86 CETP (0.65) CETP
SCHEMBL971685 0.83 CETP (0.57) CETP
SCHEMBL13691984 0.81 CETP (0.71) CETP
SCHEMBL663228 0.78 CETP (0.74) CETP
SCHEMBL665239 0.78 CETP (0.74) CETP
SCHEMBL663229 0.78 CETP (0.74) CETP
SCHEMBL665238 0.78 CETP (0.74) CETP
SCHEMBL663230 0.78 CETP (0.74) CETP
SCHEMBL27889427 0.78 CETP (0.74) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009109549-A1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-09-11 WO disclosed