SCHEMBL13691990

SCHEMBL13691990

CC1CC(C)(C)Cc2nc3c(c(-c4ccc(F)cc4)c21)C(c1ccc(C(F)(F)F)cc1)OC3C

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL971617 0.91 CETP (0.61) CETP
SCHEMBL2361563 0.86 CETP (0.47) CETP
SCHEMBL971645 0.86 CETP (0.47) CETP
SCHEMBL12445078 0.81 CETP (0.53) CETP
SCHEMBL973261 0.74 CETP (0.59) CETP
SCHEMBL12444130 0.74 CETP (0.63) CETP
SCHEMBL12921480 0.73 CETP (0.64) CETP
SCHEMBL12444148 0.73 CETP (0.64) CETP
SCHEMBL973364 0.72 CETP (0.63) CETP
SCHEMBL12445039 0.72 CETP (0.49) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009109549-A1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-09-11 WO disclosed