Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 13/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 13/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 13/20 | 0.50 |
| ▸ | GCGR | P47871 | 12/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | FRK | P42685 | 2/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69591 | 0.92 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL67121 | 0.91 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL67192 | 0.90 | MAPK11 (0.64) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL67680 | 0.90 | SMPD3 (0.51) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL69575 | 0.88 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL67437 | 0.85 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL68110 | 0.83 | FYN (0.46) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL67983 | 0.83 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL69109 | 0.82 | MAPK14 (0.46) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL85078 | 0.82 | MAPK14 (0.43) | MAPK14MAPK13MAPK12MAPK11GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115572-A2 | NOVEL HETEROCYCLIC COMPOUNDS AND USES THEROF | NOVARTIS AG (CH) | 2009-09-24 | — | — | WO | disclosed |