Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSUN3 | Q9H649 | 1/20 | 0.78 |
| ▸ | STAT3 | P40763 | 8/20 | 0.67 |
| ▸ | NPC1 | O15118 | 10/20 | 0.65 |
| ▸ | RAB9A | P51151 | 10/20 | 0.65 |
| ▸ | MEN1 | O00255 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.60 |
| ▸ | MLNR | O43193 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29074204 | 0.88 | NSUN3 (1.00) | NSUN3STAT3NPC1RAB9AMEN1 | |
| SCHEMBL23105689 | 0.84 | NPC1 (0.72) | NSUN3STAT3NPC1RAB9AMEN1 | |
| SCHEMBL1804666 | 0.83 | NPC1 (0.76) | NSUN3STAT3NPC1RAB9AMEN1 | |
| SCHEMBL11154084 | 0.82 | STAT3 (0.75) | NSUN3STAT3NPC1RAB9AMEN1 | |
| SCHEMBL11154311 | 0.81 | STAT3 (0.79) | NSUN3STAT3NPC1RAB9AMEN1 | |
| SCHEMBL29056922 | 0.80 | STAT3 (0.77) | STAT3NPC1RAB9AMEN1KMT2A | |
| Tizoxanide SCHEMBL375440 | 0.80 | STAT3 (1.00) | NSUN3STAT3NPC1RAB9AMEN1 | |
| Tizoxanide SCHEMBL29367981 | 0.80 | STAT3 (1.00) | NSUN3STAT3NPC1RAB9AMEN1 | |
| SCHEMBL872677 | 0.80 | STAT3 (0.68) | NSUN3STAT3NPC1RAB9AMEN1 | |
| SCHEMBL13694243 | 0.80 | MEN1 (0.62) | NSUN3STAT3NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221647-A1 | N-(2-THIAZOLYL)-AMIDE DERIVATIVES AS GSK-3 INHIBITORS | NOSCIRA, S.A. (ES) | 2009-09-03 | — | — | US | disclosed |
| US-20090221647-A1 | N-(2-THIAZOLYL)-AMIDE DERIVATIVES AS GSK-3 INHIBITORS | NOSCIRA, S.A. (ES) | 2009-09-03 | — | — | US | disclosed |
| WO-2007125110-A1 | N- ( 2-THIAZOLYL) -AMIDE DERIVATIVES AS GSK-3 INHIBITORS | NOSCIRA, S.A. (ES) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221647-A1 | N-(2-THIAZOLYL)-AMIDE DERIVATIVES AS GSK-3 INHIBITORS | GSK3B, GSK3A, GSKIP | NSUN3 2541/4885STAT3 1459/4885NPC1 829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.