Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14401526 | 0.83 | PSMB11 (0.40) | HPGDALDH1A1KDM4EHTT | |
| SCHEMBL13875511 | 0.83 | APP (0.56) | APPHPGDALDH1A1KDM4EHTT | |
| SCHEMBL14401518 | 0.79 | CYP1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2PDE4APDE4B | |
| SCHEMBL14401515 | 0.77 | CYP1A1 (0.42) | HPGDALDH1A1KDM4EHDAC6MEN1 | |
| SCHEMBL16070280 | 0.77 | APP (0.32) | APP | |
| SCHEMBL12451468 | 0.76 | KDM4A (0.43) | APPALDH1A1HTTMEN1KMT2A | |
| SCHEMBL18774418 | 0.76 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL19649207 | 0.75 | BACE1 (0.43) | APPMEN1KMT2A | |
| SCHEMBL21005628 | 0.75 | — | — | |
| SCHEMBL14401577 | 0.74 | KDM4E (0.38) | HPGDALDH1A1KDM4EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109457-A2 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING AT LEAST ONE DIRECT DYE COMPRISING A DISULPHIDE/PROTECTED-THIOL FUNCTION AND AT LEAST ONE SILICEOUS COMPOUND COMPRISING A THIOL FUNCTION AND METHOD USING THE COMPOSITION | L'OREAL (FR) | 2009-09-11 | — | — | WO | disclosed |
| EP-2053094-A2 | Composition for dyeing keratinous fibres comprising at least one direct dye with disulphur/thiol function and at least one polymer with thiol function and method using the composition | L'Oréal (FR) | 2009-04-29 | — | — | EP | disclosed |