SCHEMBL1369540

SCHEMBL1369540

CCCCN(C)C(=O)c1ccc(C#Cc2cc(Cl)ccc2OC(C(=O)O)C(C)(C)C)cc1S(=O)(=O)C(C)C

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1368467 0.89 PTGDR2 (0.72) PTGDR2
SCHEMBL1367989 0.88 PTGDR2 (0.68) PTGDR2
SCHEMBL1371293 0.88 PTGDR2 (0.75) PTGDR2
SCHEMBL1368835 0.87 PTGDR2 (0.80) PTGDR2
SCHEMBL12146241 0.84 PTGDR2 (0.66) PTGDR2
SCHEMBL1369045 0.78 PTGDR2 (0.75) PTGDR2
SCHEMBL1368275 0.75 PTGDR2 (1.00) PTGDR2
SCHEMBL1369235 0.75 PTGDR2 (0.90) PTGDR2
SCHEMBL1371978 0.74 PTGDR2 (1.00) PTGDR2
SCHEMBL1370540 0.74 PTGDR2 (0.62) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273769-B2 Phenoxy acetic acid derivatives MERCK SERONO SA (CH) 2012-09-25 US disclosed
US-20110288066-A1 PHENOXY ACETIC ACID DERIVATIVES MERCK SERONO S.A. (CH) 2011-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288066-A1 PHENOXY ACETIC ACID DERIVATIVES HRH2, HRH1, HRH3 PTGDR2 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.