⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404382 | 1.00 | — | — | |
| SCHEMBL153362 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28784700 | 0.98 | CYP3A4 (0.42) | — | |
| Hydrochloric Acid SCHEMBL530195 | 0.98 | CYP3A4 (0.42) | — | |
| Hydrochloric Acid SCHEMBL3965022 | 0.98 | CYP3A4 (0.42) | — | |
| SCHEMBL9921624 | 0.93 | CYP3A4 (0.39) | — | |
| SCHEMBL11920765 | 0.93 | CYP3A4 (0.39) | — | |
| SCHEMBL2557179 | 0.93 | CYP3A4 (0.39) | — | |
| Sulfuric Acid SCHEMBL7754307 | 0.92 | CYP3A4 (0.40) | — | |
| SCHEMBL23279249 | 0.91 | CYP3A4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140127762-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALPHA-SUBSTITUTED PROLINE | API CORPORATION (JP) | 2014-05-08 | — | — | US | claimed |
| EP-2041120-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG Life Sciences Ltd. (KR) | 2009-04-01 | — | — | EP | claimed |
| WO-2008007930-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2008-01-17 | — | — | WO | claimed |
| EP-1416933-B1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM INC (US) | 2008-01-02 | — | — | EP | claimed |
| JP-2007506716-A | — | — | 2007-03-22 | — | — | JP | claimed |
| EP-1670786-A1 | QUINAZOLINE DERIVATIVES | Astrazeneca AB (SE) | 2006-06-21 | — | — | EP | claimed |
| WO-2005030757-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-04-07 | — | — | WO | claimed |
| US-4493828-A | Use of thyrotropin releasing hormone and related peptides as poultry growth promotants | MERCK & CO., INC. (US) | 1985-01-15 | — | — | US | claimed |
| US-20240239852-A1 | AMYLIN RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2024-07-18 | — | — | US | disclosed |
| WO-2024077087-A2 | M24B AMINOPEPTIDASE INHIBITORS FOR CARDS INFLAMMASOME ACTIVATION | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2024-04-11 | — | — | WO | disclosed |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230331803-A1 | CO-AGONISTS OF THE GLP-1 AND AMYLIN RECEPTORS | NOVO NORDISK A/S (DK) | 2023-10-19 | — | — | US | disclosed |
| CN-111599476-B | Prediction model of hypertension, establishment method thereof and biomarker for predicting hypertension | 中南大学湘雅医院 | 2023-08-11 | — | — | CN | disclosed |
| US-20230094176-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENT AB (SE) | 2023-03-30 | — | — | US | disclosed |
| US-4581169-A | Nona-peptide and deca-peptide analogs of LHRH, useful as LHRH antagonists | SYNTEX (U.S.A.) INC. (US) | 1986-04-08 | — | — | US | disclosed |
| US-4493828-A | Use of thyrotropin releasing hormone and related peptides as poultry growth promotants | MERCK & CO., INC. (US) | 1985-01-15 | — | — | US | disclosed |
| US-4481190-A | LUTEINIZING HORMONE RELEASING HORMONE | SYNTEX (U.S.A.) INC. (US) | 1984-11-06 | — | — | US | disclosed |
| EP-0097031-A2 | Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists, their preparation and compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1983-12-28 | — | — | EP | disclosed |
| EP-0001845-A3 | ANALEPTIC TRIPEPTIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | MERCK & CO. INC. (US) | 1979-05-30 | — | — | EP | disclosed |
| EP-0001845-A2 | Analeptic tripeptides, process for their preparation and pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1979-05-16 | — | — | EP | disclosed |