Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.57 |
| ▸ | PPARA | Q07869 | 16/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000633 | 0.89 | PPARD (0.62) | PPARDPPARAALDH1A1KDM4EPPARG | |
| SCHEMBL12568380 | 0.88 | PPARD (0.58) | PPARDPPARAALDH1A1HDAC3HDAC1 | |
| SCHEMBL2000974 | 0.83 | PPARD (0.60) | PPARDPPARAALDH1A1HDAC3HDAC1 | |
| SCHEMBL12568616 | 0.79 | PPARD (0.60) | PPARDPPARAALDH1A1HDAC3HDAC1 | |
| SCHEMBL2001467 | 0.76 | PPARD (0.61) | PPARDPPARAALDH1A1KDM4EPPARG | |
| SCHEMBL12568649 | 0.75 | PPARD (0.58) | PPARDPPARAALDH1A1HDAC3HDAC1 | |
| SCHEMBL2004738 | 0.75 | PPARD (0.62) | PPARDPPARAALDH1A1KDM4EGAA | |
| SCHEMBL2000192 | 0.74 | PPARD (0.60) | PPARDPPARAALDH1A1HDAC3HDAC1 | |
| SCHEMBL13606610 | 0.73 | PPARD (0.70) | PPARDPPARA | |
| SCHEMBL12568546 | 0.73 | PPARD (0.57) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592361-B2 | (5-{3-[4-(4,5,6,7-tetrahydro-benzooxazol-2-yl)-phenoxy]-propoxy}-indol-1-yl)-acetic acid; diabetes, obesity, hyperlipidemia, and atherosclerotic disease | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |