Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.48 |
| ▸ | PPARA | Q07869 | 15/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010083 | 0.87 | PPARG (0.53) | PPARDPPARAPPARG | |
| SCHEMBL12568430 | 0.86 | PPARD (0.48) | PPARDPPARAGRM2PPARGMCL1 | |
| SCHEMBL2005566 | 0.82 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL12568696 | 0.80 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL12568704 | 0.79 | PPARD (0.53) | PPARDPPARAPPARG | |
| SCHEMBL12568727 | 0.76 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL12568702 | 0.75 | PPARD (0.48) | PPARDPPARAPPARG | |
| SCHEMBL12568443 | 0.75 | PPARD (0.48) | PPARDPPARAPPARG | |
| SCHEMBL1998643 | 0.75 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL13698944 | 0.74 | MCL1 (0.39) | PPARDPPARAGRM2PPARGMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592361-B2 | (5-{3-[4-(4,5,6,7-tetrahydro-benzooxazol-2-yl)-phenoxy]-propoxy}-indol-1-yl)-acetic acid; diabetes, obesity, hyperlipidemia, and atherosclerotic disease | BAYER PHARMACEUTICALS CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |