SCHEMBL13699363

SCHEMBL13699363

N#Cc1ccc2nn(-c3cc(CCO)cc(/C=C\C(=O)c4ccccc4)c3O)nc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
HPGD P15428 3/20 0.45
KDM4E B2RXH2 2/20 0.45
POLB P06746 1/20 0.45
ALOX15 P16050 1/20 0.45
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.45
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TYR P14679 1/20 0.37
P4HB P07237 7/20 0.36
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13700511 0.90 TYR (0.43) ALDH1A1HPGDKDM4EPOLBALOX15
SCHEMBL13700517 0.87 TYR (0.40) ALDH1A1HPGDKDM4EMAPTLMNA
SCHEMBL13699459 0.86 GRM5 (0.40) ALDH1A1KDM4EMAPK1MAPTLMNA
SCHEMBL13699493 0.86 TYR (0.40) ALDH1A1HPGDKDM4EMAPK1MAPT
SCHEMBL13700533 0.85 TYR (0.38) ALDH1A1HPGDKDM4EPOLBALOX15
SCHEMBL13700519 0.85 NPC1 (0.39) ALDH1A1HPGDKDM4EPOLBALOX15
SCHEMBL13699489 0.84 TYR (0.37) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL13700516 0.84 CYP1A1 (0.40) TYRP4HBNPC1RAB9ANFKB1
SCHEMBL13699505 0.84 MAOB (0.43) ALDH1A1POLBMAPTLMNATYR
SCHEMBL13700535 0.83 MAPT (0.42) ALDH1A1HPGDKDM4EPOLBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
EP-2103445-A1 Heat resistance improver and reversible thermosensitive recording medium Ricoh Company, Ltd. (JP) 2009-09-23 EP disclosed