Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.73 |
| ▸ | CCND1 | P24385 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | SNCA | P37840 | 4/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.63 |
| ▸ | ACHE | P22303 | 3/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045725 | 0.86 | SNCA (0.62) | SNCA | |
| SCHEMBL4331421 | 0.84 | MEN1 (1.00) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL28045722 | 0.84 | CDK4 (0.77) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL14198238 | 0.84 | CDK4 (0.77) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL5806563 | 0.83 | MEN1 (0.67) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL5803804 | 0.82 | CDK4 (0.64) | CDK4CCND1MEN1KMT2ANPC1 | |
| Cyanide SCHEMBL31484737 | 0.81 | MEN1 (0.92) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL7866515 | 0.80 | MEN1 (0.73) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL797879 | 0.80 | MEN1 (0.76) | CDK4CCND1MEN1KMT2ANPC1 | |
| SCHEMBL14303574 | 0.80 | MEN1 (0.90) | CDK4CCND1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2103602-A1 | Novel 1,2,4-triazole derivatives and process of manufacturing thereof | AEterna Zentaris GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |