Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240966 | 0.86 | NPC1 (0.50) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL74479 | 0.86 | NPC1 (0.50) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL13700644 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL13700637 | 0.85 | GAA (0.38) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL13700645 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL13699506 | 0.83 | KDM4E (0.36) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL13700641 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HPGDMAPTLMNA | |
| Diethylamine SCHEMBL7566058 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL30240896 | 0.79 | NPC1 (0.48) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL74902 | 0.79 | NPC1 (0.48) | KDM4EALDH1A1HPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324399-B2 | Heat resistance improver and reversible thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-2103445-A1 | Heat resistance improver and reversible thermosensitive recording medium | Ricoh Company, Ltd. (JP) | 2009-09-23 | — | — | EP | disclosed |