Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700511 | 0.90 | TYR (0.43) | CYP3A4TYRNPC1RAB9ANFKB1 | |
| SCHEMBL13699493 | 0.85 | TYR (0.40) | TYRNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL13700517 | 0.84 | TYR (0.40) | CYP3A4TYRNPC1RAB9ANFKB1 | |
| SCHEMBL13699506 | 0.83 | KDM4E (0.36) | NPC1RAB9AHPGDALDH1A1KDM4E | |
| SCHEMBL13699459 | 0.83 | GRM5 (0.40) | TYRNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL13700533 | 0.82 | TYR (0.38) | CYP3A4TYRNPC1RAB9ANFKB1 | |
| SCHEMBL13700519 | 0.82 | NPC1 (0.39) | TYRNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL13699489 | 0.81 | TYR (0.37) | TYRNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL13700516 | 0.81 | CYP1A1 (0.40) | TYRNPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL13699505 | 0.81 | MAOB (0.43) | TYRNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324399-B2 | Heat resistance improver and reversible thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-2103445-A1 | Heat resistance improver and reversible thermosensitive recording medium | Ricoh Company, Ltd. (JP) | 2009-09-23 | — | — | EP | disclosed |