Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 1.00 |
| ▸ | CES2 | O00748 | 5/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzil SCHEMBL27888964 | 0.98 | CES1 (0.96) | CES1CES2TDP1POLBMAPK1 | |
| Cyanide SCHEMBL10981240 | 0.94 | CES1 (0.89) | CES1CES2TDP1POLBMAPK1 | |
| SCHEMBL4603989 | 0.91 | CES1 (1.00) | CES1CES2TDP1POLBMAPK1 | |
| SCHEMBL14877375 | 0.89 | CES1 (0.80) | CES1CES2TDP1POLBMAPK1 | |
| 4-Nitrobenzoic Acid SCHEMBL3850860 | 0.88 | TDP1 (0.88) | CES1CES2TDP1POLBMAPK1 | |
| Benzophenone SCHEMBL28231509 | 0.88 | POLB (0.82) | CES1CES2TDP1POLBMAPK1 | |
| SCHEMBL229627 | 0.88 | POLB (0.82) | CES1CES2TDP1POLBMAPK1 | |
| SCHEMBL762542 | 0.87 | CES1 (0.77) | CES1CES2TDP1POLBMAPK1 | |
| SCHEMBL14877369 | 0.87 | CES1 (0.75) | CES1CES2POLBMAPK1ALDH1A1 | |
| Methane SCHEMBL29286698 | 0.86 | POLB (0.79) | CES1CES2TDP1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153194-A | Monoamine-monophenol type quinoxalinylbenzoxazin and preparation method thereof | UNIV HARBIN ENG | 2015-12-16 | — | — | CN | claimed |
| CN-105153144-A | Main-chain diamine type quinoxalinyl benzoxazine and preparation method thereof | UNIV HARBIN ENG | 2015-12-16 | — | — | CN | claimed |
| CN-102212023-B | Thioether-containing polyphenylquinoxaline compound, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2013-12-11 | — | — | CN | claimed |
| CN-102443170-A | Thermosetting polyphenylquinoxaline resin, its preparation method and application | CHINESE ACAD INST CHEMISTRY | 2012-05-09 | — | — | CN | claimed |
| CN-102212023-A | Thioether-containing polyphenylquinoxaline compound, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2011-10-12 | — | — | CN | claimed |
| US-7973034-B2 | Ameliorating toxic effects of such as cancer therapy drugs or addictive drug overdose | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2011-07-05 | — | — | US | claimed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| CN-119613344-A | High-efficiency photoinitiator, photosensitive composition and application | 武汉尚赛光电科技有限公司 | 2025-03-14 | — | — | CN | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| CN-118027346-A | Thermoplastic polyurethane elastomer material and preparation method thereof | 四川轻化工大学 | 2024-05-14 | — | — | CN | disclosed |
| US-11844847-B2 | Sulfur-containing polymerizable monomer and use thereof | SUN MEDICAL CO., LTD. (JP) | 2023-12-19 | — | — | US | disclosed |
| CN-112513016-B | Sulfur-containing polymerizable monomer and use thereof | 尚美德齿科材料有限公司 | 2023-12-19 | — | — | CN | disclosed |
| US-20230154689-A1 | SOLID ELECTROLYTE CAPACITOR AND METHOD FOR MANUFACTURING SAME | NIPPON CHEMI-CON CORPORATION (JP) | 2023-05-18 | — | — | US | disclosed |
| EP-0059649-A2 | Dental compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-08 | — | — | EP | disclosed |
| US-4162265-A | Aromatic enyne compounds and their synthesis | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1979-07-24 | — | — | US | disclosed |
| US-4147868-A | AEROSPACE POLYMERS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1979-04-03 | — | — | US | disclosed |
| US-4098825-A | ACETYLENE-SUBSTITUTED AROMATIC BENZILS AND ACETYLENE-TERMINATED QUINOXALINE COMPOSITIONS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1978-07-04 | — | — | US | disclosed |
| US-4009022-A | Selective antagonists for triazine herbicides | ROHM AND HAAS COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
| US-3956238-A | Polyetherquinoxalines | GENERAL ELECTRIC COMPANY (US) | 1976-05-11 | — | — | US | disclosed |
| US-3935239-A | Process for producing aromatic α-diketones | NEILAND OYAR YANOVICH | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11844847-B2 | Sulfur-containing polymerizable monomer and use thereof | MGMT, SETDB1, ASH2L | CES1 4243/4885CES2 4247/4885TDP1 2587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.