SCHEMBL13701110

SCHEMBL13701110

O=c1oc(-c2[nH]c3ccc(Cl)cc3c2Cc2c(-c3nc4ccccc4c(=O)o3)[nH]c3ccc(Cl)cc23)nc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ C1R P00736 4/20 0.52
▸ ELANE P08246 3/20 0.51
▸ MEN1 O00255 3/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ ALDH1A1 P00352 3/20 0.46
▸ KDM4E B2RXH2 3/20 0.46
▸ MAPT P10636 1/20 0.46
▸ APEX1 P27695 1/20 0.46
▸ NPC1 O15118 2/20 0.46
▸ RAB9A P51151 2/20 0.46
▸ F2 P00734 2/20 0.46
▸ PLG P00747 1/20 0.46
▸ KLK1 P06870 1/20 0.46
▸ PRSS1 P07477 1/20 0.46
▸ C1S P09871 1/20 0.46
▸ RXFP1 Q9HBX9 1/20 0.46
▸ HPGD P15428 1/20 0.45
▸ CASP1 P29466 1/20 0.44
▸ NPSR1 Q6W5P4 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13701081 0.88 APEX1 (0.55) C1RELANEMEN1KMT2AALDH1A1
SCHEMBL13701106 0.86 ELANE (0.60) C1RELANEMEN1KMT2AALDH1A1
SCHEMBL13701224 0.82 APEX1 (0.49) C1RELANEMEN1KMT2AALDH1A1
SCHEMBL13701127 0.81 ELANE (0.55) C1RELANEMEN1KMT2AALDH1A1
SCHEMBL13701094 0.81 ELANE (0.57) C1RELANEMEN1KMT2AALDH1A1
SCHEMBL13701088 0.78 NPC1 (0.54) C1RELANEMEN1KMT2AALDH1A1
SCHEMBL13701083 0.78 ELANE (0.53) ELANEMEN1KMT2AALDH1A1KDM4E
SCHEMBL13701080 0.78 MAPT (0.50) ELANEMEN1KMT2AALDH1A1KDM4E
SCHEMBL13700955 0.77 KDM4E (0.54) C1RELANEMEN1KMT2AALDH1A1
SCHEMBL13701125 0.76 ELANE (0.48) C1RELANEMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 — — US disclosed
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound CYP2A6, CYP2B6, XPO6 C1R 520/4885ELANE 1479/4885MEN1 1907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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