Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.61 |
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591353 | 0.84 | MAOB (0.70) | MAOBMAOAARKMT2ARAB9A | |
| SCHEMBL6589340 | 0.82 | MAOB (0.68) | MAOBMAOAARKMT2ARAB9A | |
| SCHEMBL8934483 | 0.82 | AR (0.61) | MAOBMAOAARKMT2ARAB9A | |
| SCHEMBL10063475 | 0.81 | MAOB (0.74) | MAOBMAOAARKMT2ARAB9A | |
| SCHEMBL14437593 | 0.80 | AR (0.59) | MAOBMAOAARKMT2ARAB9A | |
| SCHEMBL19000917 | 0.80 | AR (0.61) | MAOBMAOAARKMT2ARAB9A | |
| SCHEMBL28026514 | 0.79 | MAOB (0.70) | MAOBMAOAARKMT2ARAB9A | |
| SCHEMBL12617399 | 0.79 | MAOB (0.70) | MAOBMAOAARKMT2ARAB9A | |
| SCHEMBL18312160 | 0.79 | MAOB (0.70) | MAOBMAOAARKMT2ARAB9A | |
| SCHEMBL18898659 | 0.79 | MAOB (0.73) | MAOBMAOAARKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221031-A1 | NOVEL GROUP OF ESTERASES FOR THE PRODUCTION OF FINE AND SPECIALITY CHEMICALS | B.R.A.I.N. AG (DE) | 2009-09-03 | — | — | US | disclosed |