SCHEMBL1370320

SCHEMBL1370320

NCCCCC(N)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 4/20 0.58
NOD1 Q9Y239 3/20 0.45
SLC6A5 Q9Y345 1/20 0.45
GLO1 Q04760 1/20 0.43
PTGS1 P23219 1/20 0.43
GSTK1 Q9Y2Q3 1/20 0.43
NMT2 O60551 2/20 0.42
NMT1 P30419 2/20 0.42
TERT O14746 1/20 0.42
GNPAT O15228 1/20 0.42
GSR P00390 1/20 0.41
EPHX2 P34913 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1370325 1.00 FOLH1 (0.58) FOLH1NOD1SLC6A5GLO1PTGS1
SCHEMBL30099709 0.96 FOLH1 (0.56) FOLH1NOD1SLC6A5GLO1PTGS1
SCHEMBL30099563 0.94 FOLH1 (0.56) FOLH1NOD1SLC6A5GLO1PTGS1
SCHEMBL29655368 0.93 FOLH1 (0.53) FOLH1NOD1SLC6A5GLO1PTGS1
SCHEMBL30064268 0.93 FOLH1 (0.48) FOLH1GLO1PTGS1GSTK1NMT2
SCHEMBL29569049 0.93 FOLH1 (0.46) FOLH1NOD1SLC6A5NMT2NMT1
SCHEMBL30697803 0.93 FOLH1 (0.59) FOLH1NOD1SLC6A5GLO1PTGS1
SCHEMBL30099692 0.92 FOLH1 (0.56) FOLH1NOD1SLC6A5GLO1PTGS1
SCHEMBL31480035 0.91 FOLH1 (0.50) FOLH1SLC6A5GLO1PTGS1GSTK1
SCHEMBL30099585 0.91 FOLH1 (0.53) FOLH1NOD1SLC6A5GLO1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160263235-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC (CA) 2016-09-15 US disclosed
EP-2794663-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF Angiochem Inc. (CA) 2014-10-29 EP disclosed
CN-103665170-A Peptide therapeutic conjugates and uses thereof ANGIOCHEM INC 2014-03-26 CN disclosed
CN-102348723-A Peptide therapeutic agent conjugates and uses thereof ANGIOCHEM INC 2012-02-08 CN disclosed
US-20110288011-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2011-11-24 US disclosed
WO-2010063124-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2010-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160263235-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF VIP, SLC1A5, SLC47A1 FOLH1 144/4885NOD1 3097/4885SLC6A5 567/4885
US-20110288011-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF VIP, SLC1A5, SLC47A1 FOLH1 144/4885NOD1 3097/4885SLC6A5 567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.